Group B Streptococcal Infection in Jeddah, Saudi Arabia: Maternal Colonization and Neonatal Infection

Prevention of neonatal group B streptococcal infection.

Neonatal group B streptococcal infection is the primary cause of neonatal morbidity related to infection. It can often be prevented by identifying and treating pregnant women who carry group B streptococci or who are at highest risk of transmitting the bacteria to newborns. Increasing evidence and expert opinion support intrapartum treatment of women at relatively high risk of delivering an inf...

Neonatal group B b-haemolytic streptococcal infection in Kuala Lumpur.

First six cases of neonatal group B B haemolytic streptococcal sepsis in GHKL & Maternity Hospital K.L. were reported and in one third, it was fatal. Five of the cases were 'early onset' type and one was 'late onset' type. While maternal infant transmission of the disease is important in the 'early onset' type, environmental sources of infection are also significant. No gestational age or birth...

Seroepidemiology of Asymptomatic Dengue Virus Infection in Jeddah, Saudi Arabia.

BACKGROUND Although virologically confirmed dengue fever has been recognized in Jeddah, Saudi Arabia, since 1994, causing yearly outbreaks, no proper seroepidemiologic studies on dengue virus have been conducted in this region. Such studies can define the extent of infection by this virus and estimate the proportion that may result in disease. The aim of this study was to measure the seropreval...

Maternal and neonatal group B streptococcal bacteriuria.

Protection from group B streptococcal infection in neonatal mice by maternal immunization with recombinant Sip protein.

The protective potential of antibodies directed against group B streptococcus (GBS) Sip surface protein was determined by using the mouse neonatal infection model. Rabbit Sip-specific antibodies administered passively to pregnant mice protected their pups against a GBS lethal challenge. In addition, active immunization with purified recombinant Sip protein of female CD-1 mice induced the produc...